One Physics partners with healthcare organizations to build and prepare successful radiopharmaceutical therapy programs from the ground up. From radiation safety and licensing to facility planning, shielding, workflow design, and staff training, our experts help ensure your program and patient spaces are prepared to support the recommendations and requirements of radiopharmaceutical manufacturers so you’re ready to deliver safe, compliant patient care from day one.
Do you need help understanding radiopharmaceutical processes?
How are you ensuring your staff is safe around radiopharmaceuticals?
Do you have your RAM license and radiation safety protocols in place?
A complete suite of radiation safety and compliance services built specifically for sites launching or operating radiopharmaceutical programs.
Expert navigation of the NRC and Agreement state Radioactive Materials licensing process from initial application and documentation through education requirements, facility inspections, and ongoing compliance maintenance
Our RSOs work closely with physician authorized users, imaging directors, imaging managers, technologists, and administrators to ensure that radiation safety practices are practical, clearly communicated, and consistently applied across all modalities and locations
Tailored radiopharmaceutical handling and radiation safety training for nuclear medicine technologists, nursing staff, and covering radiopharmaceutical-specific protocols for each therapy your site administers
Development of site-specific written directives forms, radiation safety program policies, emergency procedures, and regulatory documentation all aligned with NRC and Agreement state RAM license requirements
Comprehensive site-specific protocols including radioactive waste management (including potential contaminants i.e. metastable Lu-177m), area survey procedures, shielding requirements, and dosimetry programs to protect clinical staff
Dedicated consulting engagements with One Physics Medical Physicists structured program assessments, regulatory strategy, and on-call expert support for sites at any stage of their radiopharmaceutical therapy program
Theranostics combines diagnostic imaging and targeted therapy into a single treatment approach. Radioactive compounds and radiopharmaceuticals are used both to identify disease sites and to deliver targeted radiation directly to cancer cells.
For healthcare facilities, administering these drugs requires specialized licensing, site infrastructure, radiation safety protocols, and trained clinical staff. The regulatory and operational requirements are substantial and growing rapidly as new therapies receive FDA approval.
Bone metastases treatment
Prostate cancer targeted therapy
Liver cancer radioembolization
Neuroendocrine tumor therapy
Thyroid gland hyperthyroid and cancer cell therapy
Pharmaceutical manufacturers provide the therapy, but the healthcare facility is responsible for establishing and maintaining the operational infrastructure necessary to administer it safely and in compliance within applicable regulations. This includes radioactive materials licensing, radiation safety procedures, waste management, staff training, shielding evaluations, and ongoing regulatory compliance.
One Physics provides dedicated Medical Physicist and Radiation Safety Officer support to take these burdens off your clinical staff so your program launches on time, stays compliant, and keeps every team member safe.
We currently support over 500+ active sites for Radiation Safety Officer services across the United States.
Theranostics programs operate at the intersection of nuclear medicine, oncology, and radiation safety, each with its own regulatory framework. Without a dedicated Medical Physicist, sites face significant compliance exposure and staff safety risk.
NRC and State-level Radioactive Materials licenses require extensive documentation, education requirements, facility inspections, and ongoing compliance reporting — a process that can take 6–18 months without expert guidance.
Radiopharmaceuticals emit ionizing radiation. Without proper handling protocols, shielding, and dosimetry programs, clinical staff face measurable occupational exposure risks.
Radioactive waste must be handled, stored, and disposed of under strict federal and state guidelines. Certain radiopharmaceutical therapy products may contain long-lived radionuclide impurities that require additional consideration for radioactive waste storage, decay-in-storage, and disposal. Our experts provide guidance throughout this process to help ensure compliant and efficient radioactive waste management while minimizing unnecessary storage time. Non-compliance carries significant penalties.
Successful theranostics programs begin with rooms updated to safely support the handling and administration of radiopharmaceuticals. One Physics partners with medical centers, architects, and project teams to evaluate existing spaces or plan new treatment areas that align with manufacturer recommendations and regulatory requirements.
Our experts provide shielding calculations, room design reviews, radiation safety assessments, workflow planning, waste management guidance, and regulatory support to help ensure patient treatment rooms, hot labs, uptake areas, storage, and adjacent spaces are prepared for safe, efficient operations.
From initial site assessment through active program support, a structured engagement is designed around your timeline and regulatory requirements.
We evaluate your facility's current infrastructure, existing licenses, staffing, and readiness to identify the specific requirements for your theranostics program — and build a roadmap to get you there.
Our physicists lead the Radioactive Materials license application process with the NRC or your state regulatory agency — managing documentation, facility amendments, and education requirements from start to approval.
We develop site-specific radiation safety protocols, written directives, waste management procedures, and emergency response plans — all documented to satisfy your RAM license requirements and NRC standards.
Clinical staff receive hands-on training in radiopharmaceutical handling, area surveys, dosimetry, and drug-specific safety procedures before your program goes live.
After launch, One Physics provides continuous Radiation Safety Officer support, annual staff training, regulatory monitoring, and dedicated consulting access as your program scales and new therapies are added.
One Physics is dedicated to transforming the health and safety of our communities by providing comprehensive medical physics and radiation safety solutions to our clients.
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